READ / 01
Methods, context, and practical notes around research questions, with sources and boundaries kept in view.
8 entries
A review of virtual-cell research, from cell foundation models and mechanistic whole-cell simulations to morphology, metabolism, spatial interactions, tissues and embryos. It surveys public data, code and benchmarks, distinguishing validated capabilities from research goals, with references and practical starting points.
Chinese body textA version-pinned guide to AlphaFold 3 on Linux GPUs, CPUs, and Apple Silicon, including installation, storage requirements, experimental backends, and limitations.
Chinese body textA guide to BindCraft2 v1.0.4 changes in antibody interfaces, induced-fit and fold-switching filters, and large-system execution, with the limits of the reported computational examples.
Chinese body textBioEmu2 combines structure prediction, equilibrium sampling and time propagation. Official demonstrations and author responses explain its potential, while binding rates, membrane-protein dynamics and hardware performance still require validation.
Chinese body textClaude coordinated a protein-design campaign that produced 318,484 computational designs and 211 tested candidates. Seventeen met the authors’ binding criteria; toxin neutralization, broad coverage and therapeutic efficacy remain unproven.
Chinese body textCLEAN Database connects enzyme-function predictions for over 55 million protein sequences with search, filtering, and mutation scoring. A guide to its uses and the limits of prediction confidence and ESM-2 scores.
Chinese body textHADDOCK3 2026.10.1 fixes a silent failure in contactairs. This guide explains the selection-expression and byres changes, added tests, and which refinement or scoring jobs merit review.
Chinese body textAn illustrated snapshot of fifteen DevDay announcements across models, persistent work, APIs, collaboration, and extensions, with links back to the official recap.
Chinese body textNo matching entries. Try another keyword or topic.